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Product Details

Place of Origin:China
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Certification:ISO,CE
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Min.Order Quantity:1 Kilograms
Price:USD $1.00 - $1.00 / Kilogram
Payment Terms:L/C,T/T

Product Description

Introduction

Name:Etizolam

Accession Number:DB09166

Type:Small Molecule

Groups:Experimental

Description

Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties.

Indication

Indicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia.

Pharmacodynamics

Etizolam is a CNS depressant with anxiolytic, anticonvulsant, sedative-hypnotic and muscle relaxant effects. It acts on the benzodiazepine site of the GABA-A receptor as an agonist to increase inhibitory GABAergic transmission throughout the central nervous system. Studies indicate that etizolam mediates its pharmacological actions with 6 to 10 times more potency than that of diazepam. Clinical human studies performed in Italy showed clinical effectiveness of etizolam in relieving symptoms in patients with generalized anxiety disorders with depressive symptoms 2,3,4. Etizolam also mediates imipramine-like neuropharmacological and behavioral effects, as well as minor effects on cognitive functioning. It is shown to substitute the actions of a short-acting barbiturate, pentobarbitol, in a drug discrimination study 8. Etizolam is an antagonist at platelet-activating-factor (PAF) receptor and attenuates the recurrence of chronic subdural hematoma after neurosurgery in clinical studies 9. It is shown to inhibit PAF-induced bronchoconstriction and hypotension 

Etizolam - Wikipedia

Etizolam (marketed under many brand names) is a thienodiazepine derivative which is a benzodiazepine analog. The etizolam molecule differs from a benzodiazepine in that the benzene ring has been replaced by a thiophene ring and triazole ring has been fused, making the drug a thienotriazolodiazepine

Etizolam | Effects of Etizolam | FRANK

Etizolam. Also called: Zoly; Sylazepam; Pasaden; Mozun; Inxity; Etizola; Etisedan; Etilaam; Eticalm; Dezolam; Depas

A case of etizolam dependence - NCBI

[1] Etizolam is a thienodiazepine anxiolytic and is said to have low tolerance and dependence liability than benzodiazepines.[2] We report a case of etizolam 

Information Sheet Etizolam - Scottish Drugs Forum

Drug overview: Etizolam is a benzodiazepine analogue, a thienodiazepene.1 It has gathered some popularity on the new psychoactive substance (NPS) market 

Etizolam vs. Xanax: What's the Difference? What You Need to

Etizolam is primarily used to treat insomnia and anxiety disorders, and it's especially good at relieving anxiety. But it's less likely to have hypnotic effects. In higher doses, it can cause hypnosis, sedation, loss of motor control, and other effects consistent with sleep aids

ETIZOLAM - DEA Diversion Control Division

Introduction: Etizolam is a thienodiazepine which is chemically related to a class of substances known as benzodiazepines. Benzodiazepines produce central 

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